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What We Know So Far About IBS After COVID-19

A review of existing research suggests that irritable bowel syndrome (IBS can develop in some people after COVID-19 infection. Studies estimate that about 7% of individuals develop IBS following SARS-CoV-2, with higher rates than in those who were not infected.
What We Know So Far About IBS After COVID-19
Photo by Christian Mackie


Paper Title: Post-Coronavirus Disease (COVID)-19 Irritable Bowel Syndrome: What We've Learned So Far.


Plain-Language Summary

The COVID-19 pandemic has brought attention to post-infection irritable bowel syndrome (PI-IBS), a condition related to SARS-CoV-2's impact on the gut and pandemic stressors. This review examines the prevalence, clinical features, and predictors of post-COVID-19 IBS, shedding light on its mechanisms and implications for treatment. Research in this area aims to enhance our understanding of the gut-brain axis, identify treatment targets, and guide personalized patient care.


Key Findings

  • Approximately 7.2% of individuals develop IBS after SARS-CoV-2 infection, with higher odds compared to non-infected individuals.
  • A significant increase in IBS prevalence, particularly IBS-M subtype, was seen during the pandemic, along with a slight rise in chronic idiopathic constipation (CIC).
  • Mechanisms contributing to post-COVID-19 IBS include ACE2-linked effects, inflammation, microbiota changes, serotonin signaling alterations, barrier dysfunction, and psychosocial stress.
  • Dyspnea and depression play a role in the pathway from COVID-19 infection to IBS, highlighting the interaction of biological and psychological factors.

Study Type

The study is a narrative review that synthesizes existing evidence on post-COVID-19 irritable bowel syndrome.


What This Means (and Doesn’t Mean)

This review underscores the link between SARS-CoV-2 infection and the development of irritable bowel syndrome, providing insights into underlying mechanisms and potential treatment strategies. It highlights the need for precise diagnostic approaches and tailored care for post-infection IBS patients. However, the study does not establish causation between COVID-19 and IBS or provide definitive treatment protocols.


Source

Disclaimer

This summary was created with the assistance of artificial intelligence and reviewed by a human prior to publication. While care is taken to ensure accuracy, errors are possible. If you notice any issues, have questions, or would like to request coverage of a specific research paper, please contact admin@long-covid.org.


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